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Ozempic for Weight Loss: Reviews, Clinical Trials, and More!

While Ozempic is often prescribed to combat type 2 diabetes, the US Food and Drug Administration (FDA) has not approved it for weight loss management. That hasn’t prevented doctors from prescribing the medication off-label for that purpose.

Here, we will explore the benefits of Ozempic, its side effects, and how it has affected the lives of many people across the United States.

Is Ozempic Safe for Weight Loss?

Ozempic is an FDA-approved prescription medication that is often used in the treatment of type 2 diabetes. The drug has an active compound known as semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist. It improves blood sugar, lowers hemoglobin A1C, and reduces the risk of cardiovascular problems.

Although Ozempic is not officially a weight loss medication, research suggests that it can help people shed a few pounds. In fact, the FDA has approved semaglutide 2.4 mg injections (Wegovy) for reducing cardiovascular risk in overweight or obese adults.

How Does Ozempic Work for Weight Loss Management?

Ozempic mimics the action of GLP-1, a naturally occurring hormone in the gut. This medication stimulates the body to produce more insulin in response to food intake and reduces the secretion of glucagon, which is responsible for increasing blood glucose levels.

All of this medical jargon may have caused confusion. What does it all mean, and how can this medication help you lose weight?

Simply put, the active compound in Ozempic, semaglutide, enhances the effects of GLP-1. It works in the following two ways:

  • This weight loss medication slows down gastric emptying, making you feel full after meals for longer.
  • It affects the hunger centers in the brain, reducing cravings and appetite.

Clinical Trials and Results: Is Ozempic Effective for Weight Loss?

Before self-administering any medication for weight loss, it’s essential to do your research. Start by reviewing the clinical trials and their results to determine the drug’s efficacy.

In 2021, researchers conducted a double-blind study to assess the impact of semaglutide on overweight or obese adults. They enrolled 1,961 participants with a body mass index (BMI) of 30 or greater and divided them into two groups: one receiving a weekly dose of the weight-loss medication and the other a placebo. All of the individuals were required to make lifestyle changes in tandem with taking the assigned treatment.

According to the trial results, the participants receiving semaglutide saw a significant reduction in their body weight (14.9%) compared to those on a placebo (2.4%).

Here are some of the benefits users experienced after 68 weeks while on this weight loss medication:

  • Reduced waist circumference
  • Better blood sugar levels
  • Improved blood pressure
  • Balanced cholesterol levels

While the medication is great for losing weight, it can also lead to adverse side effects, including nausea and diarrhea, ranging from mild to moderate in severity.

It’s important to note that during studies, more participants in the semaglutide group opted to discontinue than those receiving placebo due to gastrointestinal events.

What Are the Side Effects of Ozempic?

Almost 80% of patients with type 2 diabetes also have concurrent obesity, which makes Ozempic a fantastic and dual-benefit treatment option. Research also suggests its effectiveness in reducing major adverse coronary events.

However, taking Ozempic comes with a range of side effects, including nausea, gastric discomfort, and diarrhea, among many others. It could also lead to less common but more severe problems, such as vision changes, allergic reactions, and thyroid tumors or cancer.

This anti-obesity medication is also not safe for people with the following underlying medical conditions:

  • Pancreatitis
  • Type 1 diabetes
  • Diabetic retinopathy
  • Issues with the kidneys or pancreas
  • Multiple Endocrine Neoplasia syndrome type 2

Women who are pregnant or breastfeeding should avoid taking Ozempic. Currently, there is not enough evidence that would suggest that the medication is safe under such circumstances.

Is Ozempic the Same as Wegovy?

Due to the shortage of Wegovy in the United States and the increasing awareness around the use of semaglutide for weight loss, many have begun self-administering Ozempic. Although the two are similar types of medication, they come in different doses.

The 2021 study we mentioned earlier administered 2.4 mg of semaglutide, which is the exact dosage approved by the FDA for Wegovy. Another difference is that Ozempic is typically covered by insurance, while the other is not.

Due to the constant shortage of Wegovy in the United States, people are buying Ozempic for weight loss. Many medical experts have expressed concerns over the off-label usage of this drug, stating that those self-administering semaglutide are interfering with the availability of this type 2 diabetes medication for those who actually need it.

How Much Weight Can Patients Lose While Taking Ozempic?

While studies show that semaglutide can result in significant weight loss, it’s difficult to ascertain precisely how many pounds an individual may lose over a period of time. The answer to this question depends on many factors, including age, lifestyle, and underlying medical conditions, among many others.

According to a small study that evaluated 175 participants with a body mass index of 27 or more, weekly semaglutide injections resulted in an average weight reduction of 14 pounds over three months.

Exploring Ozempic for Weight Loss Reviews: Before and After Transformations

Ozempic has been a game-changer and is a safe form of medical weight loss among people with excess weight or obese patients. However, it requires a lifelong commitment, as stopping its use may bring back the pounds that you’ve worked so hard to shed.

Learn more about the benefits and side effects of taking Ozempic for weight loss by reading the following real-life stories:

Kimberly Tabor Flaunts Her New Slim Body After Taking Ozempic

Kimberly Tabor tried a lot of weight loss programs, including changing her diet, but she only started to drop a few pounds after taking Ozempic. Surprisingly, she started taking the medication for her type 2 diabetes.

Since Tabor was too busy trying to ensure a stable work-life balance, she didn’t focus on herself. Her diabetes led to severe obesity, which became even more troubling to control. With her time divided between managing a job and caring for her child, Kimberly resorted to fast food, leading to weight gain.

In an interview, Tabor stated that she has been able to control snacking and eat smaller portions. Since she’s been on Ozempic, Kimberly has lost significant weight.

Serafina Raskin Can Now Enjoy Certain Foods While on Ozempic

Serafina Raskin is among the many people who have found that taking Ozempic for weight loss is much easier than adhering to a restrictive diet. In an interview with NBC News, she shared that she no longer worries about eating specific foods or panics over her carbohydrate intake.

Interestingly, Serafina indulges in pasta occasionally. During the interview, she expressed that she doesn’t need to maintain a perfect diet while on Ozempic. The happiness on her face suggests the significant benefits this medication has provided her.

A key thing to note is that while some people have had positive experiences, there are a few who have complained about the side effects, such as stomach cramps, vomiting, and fatigue, prompting them to stop taking Ozempic and seek other alternative treatments.

Jeannine DellaVecchia Stops Taking Ozempic Cites “Too Many Side Effects”

In a recorded interview on Today News, Jeannine DellaVecchia, a 40-year-old hospital worker suffering from congenital adrenal hyperplasia and polycystic ovary syndrome, stated that her doctor prescribed Ozempic to manage the symptoms related to insulin resistance. Between August 2022 and February 2023, she lost more than 30 pounds.

While weight loss wasn’t DellaVecchia’s priority, the medication made her vomit uncontrollably, lose her appetite, and feel nauseous. She had to stop taking Ozempic, as the side effects were too much to handle.

Fortunately, DellaVecchia was able to maintain her weight loss by embarking on a keto diet. It goes to show that this anti-obesity medication may not be the right option for everyone.

You should always work with an experienced medical professional to determine a suitable treatment plan to help you shed a few pounds.

Gray Beard Credits Wegovy for Her Remarkable Weight Loss

Gray Beard was suffering from high blood pressure and found it incredibly difficult to lose weight until she started taking Wegovy in February 2023. Since then, the medication has helped her with blood sugar control while providing a feeling of fullness, resulting in a massive 40-pound weight loss.

While talking about her experience on Wegovy, Beard explains how she moved away from cardio and started to focus on weight training due to the medicine decreasing her muscle mass.

That’s an interesting observation, as 2023 research also suggested incorporating physical activity to compensate for the loss of muscle associated with taking anti-obesity medications.

Further studies into Ozempic can help us understand the full extent of the benefits and side effects, allowing us to take the right steps to complement this type of weight loss treatment.

Staying on Ozempic Long-term Poses Certain Challenges, Says Wendy Tell

One of the major challenges of being on Ozempic long-term is its price. Without insurance, it can cost more than $1,000 a month.

A retired school teacher, Wendy Tell, talks about her experiences with this medication. She started taking Ozempic for her type 2 diabetes. While on medication, Tell lost 25 pounds, giving her body a transformation that she thought wasn’t possible.

Unfortunately, Wendy couldn’t keep up with the $700 monthly payments because of her coverage limits, prompting her to stay off the drug. This resulted in her gaining all of the weight she had previously lost.

A major dilemma in taking Ozempic is the short supply and ridiculous costs. While anti-obesity medications are affordable all across the world, the average American pays thousands of dollars. Since insurance does not provide full coverage in many cases, it can put a dent in the patient’s wallet.

Even if you have the financial means to buy Ozempic for weight loss, its short supply can affect your treatment plan. As some studies suggest, discontinuing the medication may lead to weight regain.

Final Thoughts on Ozempic for Weight Loss

Reviews from users on Ozempic can help provide insights into how this medication works and its impact on the lives of people around the world. Losing weight can be difficult for some individuals, which is why they may have to consider taking a medical approach.

While Ozempic’s primary use is lowering blood sugar in diabetic patients, shedding a few pounds while under this medication is a much-talked-about side effect. That said, not all people experience the benefits of this drug. Some may face gastrointestinal discomfort and digestive issues.

If you’re planning to take Ozempic for weight loss, it’s important to work with an experienced medical professional. They can help you make an informed decision by explaining the risks of this medication and the proper dosage.